AMS Fact Sheet – Menopause before 40 and spontaneous premature ovarian insufficiency

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Menopause before 40 and spontaneous premature ovarian insufficiency (POI)

MAIN POINTS
  • Premature ovarian insufficiency (POI) is a loss of function of the ovaries in women who are less than 40 years old.
  • Spontaneous POI affects up to 4% of women less than 40 years and in most cases the cause is not identified.
  • Irregular/no menstrual periods or menopausal symptoms may be the only sign of POI and blood tests are needed for diagnosis.
  • POI can cause infertility and increase the risk of long-term health problems such as heart disease and osteoporosis.
  • Hormone replacement therapy is recommended until the usual age of menopause (around 51 years) to reduce the long-term risks.
  • Speak with your doctor about treatments and other options to manage any infertility and health consequences.
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